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Rebate debate redux: Revisiting 340B drug pricing

Prescription desk at US pharmacy
Photo: Spencer Platt/Getty Images

In a high-stakes struggle over the fate of the popular drug pricing program, neither the Trump administration nor safety-net hospital groups seem willing to cede the field.

On February 17, 2026, the Health Resources and Services Administration (HRSA) issued a request for information (RFI) seeking comment on the use of manufacturer rebates to establish ceiling prices for drugs in the federal 340B program.

The RFI was seen by regulatory observers as an early indication that the Trump administration intended

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